Pathogens… Just the word causes worry amongst
any person who knows what they are. And in quick, they’re a thing we all want to
steer clear of. We not too long ago got the opportunity to speak with Milan Patel, Co-founder and CEO
of PathogenDx, a Scottsdale, AZ primarily based organization which has created a disruptive
technologies: DNA-primarily based testing for cannabis as nicely as other industries.
Verify out the interview beneath to understand a lot more
about this technologies and what it indicates for cannabis growers and buyers.
CM: What is
PathogenDx – in one particular sentence, and then in depth? What is the technologies in
play right here?
Patel: In one particular sentence, PathogenDx is an Arizona biotechnology
organization that has created a disruptive DNA-primarily based technologies to test for
many pathogens (bacterial and fungal organisms that lead to contamination) in
a fraction of the time, expense and labor to guarantee cannabis, hemp, meals, ag, and
water is secure for consumption.
The globe is filled with
dangerous pathogens that increasingly threaten the security of our cannabis, hemp,
meals and water provide. And but, testing labs nonetheless rely on the Petri dishes scientists
invented more than a century ago. At PathogenDx, microbial testing has now been
brought into the modern day age. The company’s patent-winning scientists have
invented a game-altering DNA-primarily based microarray technologies (see image beneath) that
accelerates the testing identification and quantification of microbes (from
E-coli to powdery mildew)—delivering precise outcomes in just six hours without having
the will need for enrichment or DNA purification. The organization entered the Cannabis
market place to demonstrate the energy of the Ultra-fast DNA microarray to prove the
capability of delivering the quickest microbial test in the cannabis sector
when meeting the security testing regulations.
CM: The big
tool in testing has constantly been the Petri dish – why modify that now? How does DNA
come into play?
Patel: The Petri dish has been about for 140 years. Even so, testing outcomes
take very extended for the reason that with a Petri dish, you have to take a sample, enrich
any bacterial or fungal organisms in that sample, streak it on an agar culture
and wait for the cells of the bacterial or fungal pathogens to develop ahead of you
get a outcome. This can take anyplace from three days up to 7 days. When you have a
lot of samples coming into a lab, it can be extremely unwieldy.
Why modify now? – The provide chain of
cannabis, hemp, meals, agriculture and water is a lot more effective now, and with the
item moving via the provide chain substantially more rapidly to the finish consumer, the
threat is greater for the reason that a possible contaminated meals is most likely to get consumed
ahead of outcomes are obtained from petri dish testing. This is evident by the
continued increases in meals borne outbreaks in the final two-three decades, and current
examples are the meals borne outbreaks at Chipotle and the Romaine lettuce
incident. Essentially a 19th century answer can not meet the requires
and demands of these markets, and a 21st century answer is necessary
whereby outcomes are delivered more rapidly ahead of contaminated finish item gets
How does DNA come into play? – DNA comes
into play for the reason that the methodology by which the method functions is unique in
that it is a targeted method: you do not have to wait for the actual pathogen
cells to develop, you are in a position to recognize that the item is contaminated at the
molecular level, and you can get a outcome in hours.
Patel: The greatest threats facing farmers and their cannabis/ hemp crops is
continual contamination inside grows with a higher level of presence of each
bacterial and fungal microbes in the finish sample. In addition, we are beginning
to see enhanced presence of viruses – specially for hemp farmers – which is
wreaking havoc as petri dish testing can not test for viruses. This outcomes in
catastrophic losses each from an financial standpoint, as nicely as yield
CM: Even although
PathogenDx was created for hemp and cannabis, you say it can be utilized to
test other agricultural crops, water, even meat and dairy places. Will the similar
test and process be utilized for unique items what else does PathogenDx will need
to do to enter the Meals and Dairy sphere?
Patel: We have created the technologies universally applicable to many markets
as nicely as ubiquitous, in that at the base level, it is one particular method. Irrespective of whether
you are testing cannabis, romaine, milk, water or something else, the method is
successfully the similar. The content material of the kits are mainly the similar, but
from time to time enhanced with unique bacterial or fungal organisms that are
certain to that sector.
presently submitting the use of the technologies as a certified approach to the
AOAC for meals and environmental testing at the federal level. We count on to have
certification by mid-2020, and after that occurs, PathogenDx will have access
to a $30B market place. In addition, we are establishing a test that can test up to 20
pathogens that are presently causing high quality troubles in the milk and dairy
sector. We program to introduce a item in 2020 for this market place.
CM: What’s subsequent
for PathogenDx in 2020? Exactly where else do you see application of this technologies?
Patel: We are expanding the applications of the technologies into the Meals,
Environmental, Dairy markets, as nicely as introducing a plant pathogen kit that
will broaden the testing capability in cannabis, hemp and Agriculture. The technologies has possible into the substantially bigger clinical
diagnostics with a multitude of clinical applications. At the present time, the
organization is operating with quite a few collaborators to evaluate crucial market place